Welcome to
AM Chemicals
Supplier of solid supports and reagents for robust oligonucleotide synthesis.
Perfect Tools for Pristine Oligos
Established in 2003, AM Chemicals is a key player in the arena of universal solid supports and reagents for oligonucleotide synthesis. The stringent product specifications as well as batch to batch consistency of each of the products are achieved through exceptional internal quality control processes. We offer high quality products and an uncompromising commitment to excellence in our technical support.
Products
1
Solid Supports
Our advanced universal solid supports eliminate the use of nucleosidic solid supports. The majority of oligonucleotides may be synthesized starting with a single universal solid support regardless of the 3′-terminal nucleoside to be synthesized. The unique design of our universal solid supports insures their unparalleled performance in the synthesis of oligonucleotides.
2
Phosphoramidites
The universal phosphoramidite reagent eliminates the need of using nucleosidic solid supports. Regardless of the desired 3'-terminal nucleoside, most oligonucleotides can be synthesized starting with an OH- or NH2-functionalized solid support material by using the universal phosphoramidite.
The non-nucleosidic phosphoramidites are used to incorporate functional groups (e.g. GalNAc, Cholesteryl, tocopherol, etc) at any desired position of oligonucleotides for efficient cellular uptake.
3
Reagents
Our sulfurization agent DDTT, offers extremely high yields in the preparation of DNA and RNA phosphorothioates and affords excellent stability in solution.
Oligonucleotides Radiolabeling Service
AM Chemicals offers services in expert synthesis of ¹⁴C, ³⁵S, and ³H radiolabeled oligonucleotides and their phosphorothioate analogs. We synthesize radiolabeled, protected nucleoside phosphoramidite reagents required for the incorporation of the desired radiolabels into oligonucleotides, carry out oligo synthesis, deprotect, purify, and desalt the target radiolabeled oligonucleotides.
Connect with us
